|
KMID : 0384119900100020483
|
|
Korean Journal of Clinical Pathology
1990 Volume.10 No. 2 p.483 ~ p.488
|
|
|
Comparison of the Two Different Hemapheresis Systems -Plateletaphereis and Changes of Acetylcholine Receptor Antibody Titer in a Case of Myasthenia Gravis Patient during the TPEs-
|
|
J. S. Lee
J. S. Kim/K. N. Lee/D. W. Kim
|
|
|
Abstract
|
|
|
|
Cell separators are automated centrifugation devices which are operated on the principle of either continuous or intermittent flow. Now, cell-separating devices have been used by many hospitals and community blood centers to allow the collection of platelets or leukocytes from donor or removal unnecessary materials for patients. From the period of mid-Feb. to June, 1990, two different hemapheresis systems were evaluated on the 43 cases at the department of clinical pathology, Guro-hospital, Korea University. Among these, 19 cases were analyzed by using intermittent flow system, Hemonetics V50, and 24 cases by using continuous flow system, COBE-Spectra?. The purpose of this comparative study in using the two different hamapheresis systems were to figure out the adaptability of these systems to our hospital through evaluating the plateletapheresis and therapeutic plasma exchanges. Furthermore, through 4 times of therapeutic plasma exchange in 3 days interval for a myasthenia gravis patient has been applied for the removal of acetycholine receptor antibody. For the identification of striation of nerve ending, indirect immunofluorescence technique has been performed on rat`s thigh muscle with FITC-labelled anti-human immunoglobulin. When therapeutic plasma exchange hs been applied from the 1st to the 4th TPE, it has been found that the acetylcholine receptor antibody titer has been reduced gradually.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|